NINTEDANIB AND DASATINIB TREATMENTS INDUCE PROTECTIVE AUTOPHAGY AS A POTENTIAL RESISTANCE MECHANISM IN MPM CELLS

Nintedanib and Dasatinib Treatments Induce Protective Autophagy as a Potential Resistance Mechanism in MPM Cells

Malignant pleural mesothelioma (MPM) is a rare type of cancer with a grim prognosis.So far, no targetable oncogenic mutation was identified in MPM and Extractors biomarkers with predictive value toward drug sensitivity or resistance are also lacking.Nintedanib (BIBF1120) is a small-molecule tyrosine kinase inhibitor that showed promising efficacy p

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About the Brilliant Political Insight of F.M. Dostoevsky

Any state moves towards progress with the strength and aspirations, thoughts and works of the best sons who guide the country and determine its path.F.M.Dostoevsky was boxes not only a writer, philosopher, subtle psychologist, but also a statesman.Many works are known where he discusses the place of Russia in the world, the need to take a higher an

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